Research groups
About 50 research groups participate in the research school 'Cancer Genomics & Developmental Biology', most of which are part of the Focus and Mass area 'Growth and Differentiation'. They include groups that participate in the UMCU research lines Biomedical Genetics and Oncology, all groups of the Hubrecht Institute for Developmental Biology and Stem Cell Research and various groups from the Science Faculty of Utrecht University.
Biomedical Genetics (UMCU) | |
| Bos/Zwartkruis | Function and molecular mechanisms of Ras family proteins in processes related to cancer |
| Brenkman | Metabolomics and dietary restriction mediated healthy ageing |
| Burgering/Dansen | Signalling by the PI-3 kinase/PKB/Foxo pathway |
| Coffer | |
| Cuppen/Ophof/Koeleman | The genetics of complex traits |
| Fauser | Regulation of ovarian function, early development and implantation |
| Holstege | Genome control |
| Höppener | Type 2 diabetes mellitus |
| Kalkhoven | Transcription regulation in adipogenesis |
| Klumperman | Membrane traffic and fly development |
| Kops | Dynamic control of chromosome segregation |
| Maurice | Cell biology of Wnt signalling in development and cancer |
| Reggiori | Autophagy and the process of autophagosome formation |
| Timmers | Regulation of transcription and chromatin |
| Van der Sluijs | Role of endosome-lysosome secretion in brain and immune system |
| Van Mil | The role of the nuclear receptor FXR in gastro-intestinal disease |
| Verhoeven | Amino acid and vitamin metabolism in the central nervous system |
| Vermeulen | Quantitative proteomics and chromatin biology |
Oncology (UMCU) | |
| Borel Rinkes/ Kranenburg | Liver metastases of colon cancer |
| Derksen | Breast cancer development and progression |
| Giles | Understanding kidney cancer |
| Lens | The chromosomal passenger complex in cell division |
| Medema | Cell cycle checkpoints and cancer |
| Rowland | Building sister chromatid cohesion |
| van Diest | Hypoxia in breast cancer development and progression |
| Voest | Microenvironment, angiogenesis, and mutations in cancer |
Hubrecht Institute (KNAW & UMCU) | |
| Bakkers | Cardiac development and genetics |
| Berezikov | Small RNA biology |
| Clevers | Wnt signaling and cancer |
| Creyghton | Epigenetics and stem cell development |
| Cuppen | Genome biology |
| de Laat | Biomedical genomics |
| de Rooij | Dynamics of cell adhesion |
| den Hertog | Protein-tyrosine phosphatases in development |
| Deschamps | Genetics of morphogenesis during axial elongation in the mouse embryo |
| Geijsen | Pluripotent stem cells in development and disease |
| Guardavaccaro | Ubiquitin ligases and cancer |
| Ketting | RNA silencing |
| Knipscheer | Molecular mechanism and regulation of DNA repair |
| Korswagen | Mechanism of Wnt signaling in C. elegans |
| MacInnes | Translation and cancer |
| Rabouille | Regulation of secretion during development |
| Schulte-Merker | Genetic analysis of vertebrate organogenesis |
| van Rheenen | Cancer biophysics |
| Zivkovic | Zebrafish brain development and homeostasis |
Biology (UU) | |
| Akhmanova | Cell biology: cytoskeletal dynamics |
| Boxem | Protein-protein interaction networks underlying cell polarity |
| Hoogenraad | Molecular neuroscience: protein trafficking and synapse function |
| Scheres | Root development in Arabidopsis |
| Schulz | Molecular regulation of cell proliferation and differentiation in the gonads |
| Snel | Evolutionary Genomics and Integrative Bioinformatics |
| van den Heuvel | Developmental control of cell division |
Chemistry (UU) | |
| Braakman | Protein folding in the ER |
| Heck | Proteomics and biomolecular mass spectrometry technologies |
Veterinary Medicine (UU) | |
| De Bruin | E2F signalling in vascular development, tissue regeneration, and cancer |