Research Group BEREZIKOV

Hubrecht Institute for Developmental Biology and Stem Cell Research
Contact: Dr. Eugene Berezikov
E-mail: e.berezikov@hubrecht.eu
Website: http://www.hubrecht.eu/research/berezikov/index.html

General research focus: Small RNA biology

MicroRNAs and other small RNAs are now recognized as key regulators of various cellular processes but their specific functions are largely unknown. We combine computational and experimental approaches to study the repertoire, biological roles and evolution of small RNAs in animals and plants. In the nematode C. elegans we study how miRNAs contribute to the development of the nervous system. In the flat worm Macrostomum lignano – an emerging model organism for regeneration and stem cell research – we are developing genomic tools and resources, including de novo genome sequencing and annotation, to study roles of small RNAs in the maintenance and differentiation of neoblasts.

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